The timetable for Metabolomics 2014 can be downloaded here.

The quickguide to events can be downloaded here.

The organisers reserve the right to modify the contents at anytime.

Workshops I

10:50-12:10 Dai-ichi Tsuru Effective Metabolomics Software: From Design to Practice

10:50-12:10 Marica Hall Metabolomics Measurement Technology and Application & Introduction to Worldwide Networks (JST-NSF)

Luncheons

12:30-13:20 Dai-ichi Tsuru LECO

12:30-13:20 Marica Hall Bruker

Workshops II

13:40-16:40 Dai-ichi Tsuru  Early-career Member Network of Metabolomics Society

13:40-16:40 Marica Hall  Metabolomics data standards, data capture and exchange

Opening Ceremony, Society Awards & Plenary Lecture

Marica Hall

17:00-17:10 Welcome to Tsuruoka and the 10th Annual Conference. Masaru Tomita (Keio University)

17:10-17:20 Welcome to the Metabolomics Society. Mark Viant (President of the Society)

17:20-17:30 Welcome to Early-career Member Network of the Society. Sastia Putri (Chair of the Early-career Members Network)

17:30-17:40  Award Ceremony (Honorary Fellowships, Best Publication Awards)

17:40-18:20 Plenary Lecture:Metabolomics revolutionizes phytochemical genomics and crop improvement. Kazuki Saito (RIKEN CSRS, Chiba University, Japan)

Keynote Session

08:40-09:20 Dai-ichi Tsuru Plenary:Natural variation of a signalling lipid. Markus Wenk (National University of Singapore)

09:30-10:10 Dai-ichi Tsuru Use of metabolomics in systems biology: from data to understanding. Bas Teusink (University of Amsterdam, the Netherlands) 

09:30-10:10 Marica Hall From mice to man and back again: applications of metabolomics to understand type 2 diabetes and obesity. Julian L Griffin (University of Cambridge, UK)

Session 2A-D: Flux, Microbiology & Parasitology

Dai-ichi Tsuru

Choong Hwan Lee & David Watson

10:30-10:45 2A-D1: Identification of the metabolic reprogramming underlying metastasis in prostate cancer by combining multi-omic approach and model-driven data analysis. Marta Cascante (University of Barcelona, Spain)

10:45-11:00 2A-D2: OpenMebius: An Open source software for metabolic flux analysis. Hiroshi Shimizu (Osaka University, Japan)

11:00-11:15 2A-D3: Quantitative metabolic modeling for biofuel production at the Joint BioEnergy Institute. Hector Garcia Martin (Lawrence Berkeley National Lab, USA)

11:15-11:30 2A-D4: Stable-isotope labelled metabolomics for network-wide discovery of stage-specific pathways in Trypanosoma brucei. Darren Creek (Monash University, Australia)

11:30-11:45 2A-D5: An altered M. tuberculosis metabolome induced by katG mutations resulting in drug resistance. Du Toit Loots (North-West University, South Africa)

11:45-12:00 2A-D6: LC-HRMS fingerprinting: an innovative strategy to investigate bacterial metabolome during cheese ripening. Clementine Le Boucher (INRA, France)

Session 2A-M: Drug & Medicine

Marica Hall

Rima Kaddurah-Daouk & Martin Robert

10:30-10:45 2A-M1: Ceramide metabolism in the liver and its role in two lysosomal lipidoses - drug-induced phospholipidosis (DIPL) and Sandhoff disease (SD). Emmanuelle Lecommandeur (University of Cambridge, UK)

10:45-11:00 2A-M2: In Search of Metabolic Somnogens: A Unique Signature of Sleep Restriction from Blood in Rats. Arjun Sengupta (University of Pennsylvania, USA)

11:00-11:15 2A-M3: Activation of Fatigue Metabolic Pathway Induces Hepatic Inflammation in a Rat Model of Fatigue. Satoshi Kume (RIKEN Center for Life Science Technologies, Japan)

11:15-11:30 2A-M4: Metabolomics biomarkers of doxorubicin-induced cardiac injury in B6C3F1 mice. Laura K. Schnackenberg (NCTR, US FDA)

11:30-11:45 2A-M5: Metabolomics used as a tool to investigate the signature of etanercept treatment response in a psoriasis patient cohort. Nicholas Rattray (The University of Manchester, UK)

11:45-12:00 2A-M6: Using metabolomics to determine the modes of action of new antibiotics. Isabel Vincent (Glasgow University, UK)

Luncheons

12:30-13:20 Dai-ichi Tsuru Agilent

12:30-13:20 Marica Hall Shimadzu

Session 2P-D: Cancer

Dai-ichi Tsuru

Tomoyoshi Soga & Marta Cascante

13:40-14:00 2P-D1: Oncometabolites: Linking Altered Metabolism With Cancer? Patrick Pollard (University of Edinburgh, UK)

14:00-14:20 2P-D2: Finding the right path: Constructing a temporal network of RAS activity in cancer. Emily Armitage (Universidad San Pablo CEU, Spain)

14:20-14:40 2P-D3: Lipidomic profiling reveals a reconfiguration of sphingolipid metabolism that drives glioma angiogenesis and malignancy. Anthony Don (University of New South Wales, Australia)

14:40-15:00 2P-D4: Enhanced pyruvate carboxylation is crucial to non-small cell lung cancer proliferation and anabolism. Teresa Fan (University of Kentucky, USA)

Session 2P-M: CVD, Diabetes & Neuroscience

Marica Hall

Matej Oresic & Jules Griffin

13:40-13:55 2P-M1: Longitudinal metabolome en route to type 1 diabetes: potential role of gut microbiota and metabolic vulnerability in the early disease pathogenesis. Matej Oresic (Steno Diabetes Center, Finland)

13:55-14:10 2P-M2: Large scale metabolomics in clinical epidemiology. Oliver Fiehn (UC Davis, USA)

14:10-14:25 2P-M3: Examining the effects of metformin in a large clinical cohort and HepG2 and 3T3-L1 treated cells using untargeted LC-MS metabolomics. Emma Boulton (University of Glasgow, UK)

14:25-14:40 2P-M4: Metabolome and lipidome features of human brain development. Kasia Bozek (CAS-MPG Partner Institute for Computational Biology, China)

14:40-14:55 2P-M6: Accumulation of metabolic syndrome risk factors and plasma amino acids and their related metabolites: Tsuruoka Metabolomic Cohort Study. Toru Takebayashi (Keio University School of Medicine)

Poster Session I

15:00-17:00 Marica East For details see the poster page.

15:00-17:00 Dai-ichi Ho-oh For details see the poster page.

Evening Session

17:00-18:20 Dai-ichi Tsuru Thermo Scientific (No registration required)

Keynote Session

08:40-09:20 Marica Hall Plenary: Making metabolomics matter. David S Wishart (University of Alberta, Canada)

09:30-10:10 Dai-ichi Tsuru Metabolomics imaging mass spectrometry in clinical research. Mitsutoshi Setou (Hamamatsu University School of Medicine, Japan)

09:30-10:10 Marica Hall Metabolomics and the measurement of the exposome in epidemiological studies on cancer risk. Augustin Scalbert (International Agency for Research on Cancer, France)

Session 3A-D : Data Analysis, Networks

Dai-ichi Tsuru

Eiichiro Fukusaki & Masahiro Sugimoto

10:30-10:44 3A-D1: Complimentary LC- and GC-Mass Spectrometry Techniques Provide Broader Coverage of the Metabolome. Baljit Ubhi (AB Sciex, USA)

10:44-10:58 3A-D2: An advanced computational and database framework for the compound identification in untargeted metabolomics. Robert Mistrik (HighChem, Slovakia)

10:58-11:12 3A-D3: MS DIAL: Untargeted metabolomics software for data independent LC-MS/MS and mass spectral deconvolution: application to algae metabolomics. Hiroshi Tsugawa (RIKEN Center for Sustainable Resource Science, Japan)

11:12-11:26 3A-D4: MASTR-MS: A web-based collaborative Laboratory Information Management System (LIMS) for Metabolomics. Saravanan Dayalan (University of Melbourne, Australia)

11:26-11:40 3A-D5: Data-driven sample size determination for human metabolic phenotyping studiesBenjamin Blaise (Hospices Civils de Lyon, France)

11:40-11:54 3A-D6: Searching PubChem with tandem mass spectrometry data: Teaming molecular fingerprint prediction and fragmentation trees. Sebastian Boecker (Friedrich Schiller University Jena, Germany)

11:54-12:08 3A-D7: Systematic approaches for identification and removal of non-biological sources of variation in metabolomics data. Rohan Benjamin Hugh Williams (National University of Singapore, Singapore)

Session 3A-M: Nutrition, Environment & Model Organism

Marica Hall

Mark Viant & Roy Goodacre

10:30-10:42 3A-M1: Characterization of food products by GCxGC with TOFMS and GC with high resolution TOFMS: a food-omics approach. Jeff Patrick (LECO Corporation, USA)

10:42-10:54 3A-M2: A metabolomics approach shows that green tea extract attenuates UVB-induced skin metabolite alterations in mice. Eun Sung Jung (Konkuk University, South Korea)

10:54-11:06 3A-M3: Non-targeted metabolite profiling discriminates diet-specific biomarkers for consumption of whole grains, fatty fish and bilberries. Kati Hanhineva (University of Eastern Finland, Finland)

11:06-11:18 3A-M4: The secret life of the Mediterranean Lake Medee, the largest deep sea salt saturated formation in the world. David Rojo (University CEU San Pablo, Spain)

11:18-11:30 3A-M5: Differential lipid and metabolite levels in response to spawning-induced inappetence in Atlantic salmon Salmo salar. McKenzie Smith(Georgia Tech, USA)

11:30-11:42 3A-M6: A metabolomic approach to assess neurotoxic effects of imidacloprid on the freshwater snail Lymnaea stagnalis. Sara Tufi (VU Amsterdam, Netherlands)

11:42-11:54 3A-M7: Using omics for identification of the mechanism of the toxic action for perflourononanoic acid. Kasper Skov (Technical University of Denmark, Denmark)

11:54-12:06 3A-M8: Metabolome analysis of Drosophila melanogaster during embryogenesis. Thuy An Phan Nguyen (Osaka University, Japan)

Luncheons

12:30-13:20 Dai-ichi Tsuru ABSCIEX

12:30-13:20 Marica Hall HMT

Session 3P-D: Young Researchers 1

Dai-ichi Tsuru

Tim Ebbels & Darren Creek

13:40-13:55 3P-D1: Construction of a metabolome library for transcription factor-related single gene mutants of Saccharomyces cerevisiae. Zanariah Hashim (Osaka University, Japan)

13:55-14:10 3P-D2: Metabolomics-based semi-rational identification of gene targets conferring 1-butanol tolerance in Saccharomyces cerevisiae. Shao Thing Teoh (Osaka University, Japan)

14:10-14:25 3P-D3: Quantitative Analysis of Stressed Caenorhabditis elegans using Isotopic Ratio Outlier Analysis. Gregory S Stupp (University of Florida, USA)

14:25-14:40 3P-D4: Global Metabolomic Analysis of 13C-enriched Mixtures using INADEQUATE. Chaevien S Clendinen (University of Florida, USA)

14:40-14:55 3P-D5: Classification of reliable MetFrag candidate identifications for tandem mass spectra from selected lipid samples. Christoph Ruttkies (Leibniz Institute of Plant Biochemistry, Germany)

Session 3P-M: Young Researchers 2

Marica Hall

Dan Bearden & Robert Hall

13:40-13:55 3P-M1: Characterization of the Sweat Metabolome in Screen-Positive Cystic Fibrosis Patients. Adriana Nori de Macedo (McMaster University, Canada)

13:55-14:10 3P-M2: Fatty acid profiling in breast cancer biomarker discovery by GC-MS. Huai-Hsuan Chiu (National Taiwan University, Taiwan)

14:10-14:25 3P-M3: Metabolome and transcriptome changes in human, macaque and mouse brain development. Hindrike Bammann (CAS-MPG Partner Institute for Computational Biology, China) 

14:25-14:40 3P-M4: Metabolomics analysis reveals large effects of uremic toxin in heart failure outcome. Cheng-Cheng Lin (Chang Gung University, Taiwan)

14:40-14:55 3P-M5: Metabolic changes in stress-tolerant transgenic rice overexpressing calmodulin. Surachat Tangpranomkorn (Chulalongkorn University, Thailand)

Poster Session II

15:00-17:00 Marica East For details see the poster page.

15:00-17:00 Dai Ichi Ho-oh For details see the poster page.

Evening Session

17:00-18:20 Marica Hall ABSCIEX  (No registration required)

Keynote Session

08:40-09:20 Dai-ici Tsuru Googling biology using gene networks. Insuk Lee (Yonsei University,South Korea)

08:40-09:20 Marica Hall Identifying novel salinity tolerance mechanisms by spatial analysis of lipids in barley roots. Ute Roessner (University of Melbourne, Australia)

Session 4A-D: New Technology

Dai-ichi Tsuru

Robert Mistrik & Douglas Murray

09:30-09:50 4A-D1: A novel multi-platform software tool (MUSCLE) for the robust, objective and automated optimisation of targeted LC-MS/MS analyses. Mark Viant (University of Birmingham, UK)

09:50-10:10 4A-D2: CSPP networks aid the detection of in vivo substrates and products of enzymes. Kris Morreel (VIB Plant Systems Biology, Belgium)

10:10-10:30 4A-D3: Comprehensive two-dimensional liquid chromatography: a new technique for for high-resolution metabolomics? Oliver Jones (RMIT Univeristy, Australia)

Session 4A-M: Plant Physiology

Marica Hall

Kazuki Saito & Oliver Fiehn

09:30-09:45 4A-M1: Integrated Metabolomics, Gene Expression, and GWAS Identify New Saponin Biosynthetic Genes in Medicago truncatulaLloyd Sumner (The Samuel Roberts Noble Foundation, USA)

09:45-10:00 4A-M2: Metabolomic exploration toward understanding of key cellular events leading to wax ester fermentation in Euglena gracilisTakumi Ogawa (Osaka Prefectural University, Japan)

10:00-10:15 4A-M3: Monitoring primary carbon metabolism in mature Arabidopsis thaliana leaves. Pernilla Linden (Swedish University of Agricultural Sciences, Sweden)

10:15-10:30 4A-M4: Untargeted metabolomics of Habanero pepper (Capsicum chinense Jacq. var. Orange) fruits subject to Nitrogen and Phosphorus deficiency. Carlos Rodriguez-Lopez (Tecnologico de Monterrey, Mexico)

Session 4P-D: Omics Integration

Dai-ichi Tsuru

Kenji Nakahigashi & Natsumi Saito

10:50-11:06 4P-D1: A unique brain lipidome and metabolome biosignature in alzheimer disease. Giuseppe Astarita (Waters Corporation, USA)

11:06-11:22 4P-D2: 13C-based Metabolomics: Integrating LC-MS IROA with NMR. Arthur Edison (University of Florida, USA)

11:22-11:38 4P-D3: MetaboLights: Open access metabolomics repository and reference data. Reza Salek (EMBL-EBI, UK)

11:38-11:54 4P-D4: Reconstruction of global signal flow of insulin from phosphoproteome and metabolome data. Katsuyuki Yugi (University of Tokyo, Japan)

11:54-12:10 4P-D5: A catalog of human metabolic individuality. Gabi Kastenmuller (Helmholtz Center Munich, Germany)

Session 4P-M: Crops

Marica Hall

Ute Roessner & Akira Oikawa

10:50-11:06 4P-M1: Composition and metabolite differences between near-isogenic gm and conventional maize are associated more with back-crossing than with the gm traits. Mark Leibman (Monsanto Company, USA)

11:06-11:22 4P-M2: The application of metabolomics to the biochemical phenotyping of staple crops from developing countries. Elisabete Carvalho (Royal Holloway University of London, UK)

11:22-11:38 4P-M3: GC-MS based metabolite profiling of barley kernels - impact of induced drought-stress. Alexandra Wenzel (Technische Universitaet Muenchen, Germany)

11:38-12:54 4P-M4: Combining metabolomic profiling and sensory evaluation to understand consumer perception of rice flavor. Venea Dara Daygon (University of Queensland, Australia)

11:54-12:10 4P-M5: Allelopathy in canola. Md Asaduzzman (Charles Sturt University, Australia) NO SHOW

Luncheons

12:30-13:20 Dai-ichi Tsuru Thermo Scientific

12:30-13:20 Marica Hall Waters

Closing Ceremony, Conference Awards & Plenary Lecture

Marica Hall

13:40-14:20 Plenary Lecture: A GoogleMap-type view of specialized molecules from microbes, their communities and hosts including people. Pieter C Dorrestein (University of California San Diego, USA)

14:20-14:30 Conference Awards Ceremony (Tim Ebbels, Chair of the Conference & Training committee)

14:30-14:40 San Francisco 2015 Conference (Oliver Fiehn, Chair of the 2015 meeting)

14:40-14:50 Closing remark (Mark Viant, President of the Society)

Kazuki Saito
Kazuki Saito is one of the pioneers in the field of plant metabolomics and uses an integrated approach that includes functional genomics and transcriptomics. For his distinguished research, he was awarded The Prize for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, Japan, in 2010, and The Award for Distinguished Research from the Japanese Society for Plant Cell and Molecular Biology in 2011. He was also selected as one of American Society of Plant Biologists (ASPB) TOP AUTHORS in 2010.
Metabolomics revolutionizes phytochemical genomics and crop improvement
(Marica Hall, Jun 23rd, 17:40)

Abstract: Kazuki Saito

Markus R WenkMarkus Wenk spearheads novel approaches in systems scale analysis of lipids and their interactors (lipidomics) and is recognized as one of leading investigators worldwide in this emerging field (www.lipidprofiles.com). He established SLING, the Singapore lipidomics incubator, an interdisciplinary program dedicated to innovation, education and partnership in lipidomics research at the National University of Singapore (NUS, www.sling.nus.edu.sg). Markus has published more than 130 research articles, several book chapters and is an inventor on 6 patent applications.
Natural variation of a signalling lipid
(Dai-ichi Tsuru, June 24th, 08:40)

Abstract: Markus Wenk

Bas Teusink
Bas Teusink obtained his PhD in biochemistry (1999) and is currently Professor in Systems Bioinformatics at the Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam. His group is interested in the understanding and subsequent exploitation of regulation of biological networks, metabolic networks in particular. He combines quantitative experimentation with modeling of metabolism at the molecular, genome and cellular scale.
Use of metabolomics in systems biology: from data to understanding
(Dai-ichi Tsuru, Jun 24th, 09:30)

Abstract: Bas Teusink


Jules Griffin
Jules Griffin holds a joint appointment between the UK Medical Research Council Human Nutrition Research and the University of Cambridge. He is also an Honorary Professor at Imperial College London (2012-2015) and was a visiting professor at the University of Cagliari, Sardinia, Italy (2011-2012). The programme of research focuses on the development of metabolomics and lipidomics tools to investigate aspects of the Metabolic Syndrome. In particular his team has an interest in identifying biomarkers that stratify patients according to risk factor of the Metabolic Syndrome and understand the associated underlying mechanisms.

From mice to man and back again: applications of metabolomics to understand type 2 diabetes and obesity
(Marica Hall, June 24th, 09:30)

Abstract: Jules Griffin

Wishart-Lab-20121026-Wishart-DSC 5661

David Wishart began work in metabolomics in 1999. From 2006-2009, he led the “Human Metabolome Project” (HMP), a multi-university, multi-investigator project that catalogued all of the known metabolites in human tissues and biofluids. The results from this project has been archived on a freely accessible web-resource called the Human Metabolome Database (HMDB). Dr. Wishart has continued to add to this work through periodic database updates and a number of publications describing the human serum, urine and cerebrospinal fluid metabolomes. Over the last 5 years his major focus has been on bringing metabolomics out from the lab and into clinical practice. Dr. Wishart currently directs the Metabolomics Innovation Centre (TMIC), Canada’s national metabolomics platform.
Making Metabolomics Matter
(Marica Hall, Jun 25th, 08:40)

Abstract: David Wishart

SCALBERT Augustin
Augustin Scalbert is Head of the Biomarkers Group at the International Agency for Research on Cancer (IARC, Lyon, France; www.iarc.fr). His current research focuses on the exposome and the identification of novel biomarkers of exposures through metabolomics to study the etiology of cancers in large cohorts. His research on plant polyphenols has received large attention from the scientific community. He has been identified as a Highly Cited Researcher in the field of Agriculture (ISI Thomson, 2005).
Metabolomics and the measurement of the exposome in epidemiological studies on cancer risk
(Marica Hall, Jun 25th, 09:30)

Abstract: Augustin Scalbert

Mitsutoshi Setou2
Mitsutoshi Setou, MD, received his PhD degree in Medicine in 2001 from the University of Tokyo and since 2008 he is Professor and Chairman of the Department of Cell Biology and Anatomy at the Hamamatsu University School of Medicine. His field of research is molecular anatomy and cell biology with emphasis on characterization of longevity at molecular level and age related diseases. His research interests include development and applications of imaging mass spectrometry (IMS) in biology with “omics” technologies. He is co-author of over 140 peer reviewed papers (having more than 3400 cumulated citations), 14 book chapters, 4 granted patents and is the editor of a book on IMS.
Metabolomics imaging mass spectrometry in clinical research
(Dia-ichi Tsuru, Jun 25th, 09:30)

Abstract: Mitsutoshi Setou

Ute Roessner
Ute Roessner has obtained her PhD in Biochemistry at the MPI for Molecular Plant Physiology in Germany, where she developed novel GC-MS methods to analyse metabolites in plants. Together with the application of sophisticated data mining the field of metabolomics was born and is today an important tool in biological sciences, systems biology and biomarker discovery. In 2003 she moved to Australia where she established a GC-MS and LC-MS based metabolomics platform as part of the Australian Centre for Plant Functional Genomics for which she now leads the node at the University of Melbourne. In addition, since 2007 A/Prof. Roessner has been involved in the setup of Metabolomics Australia (MA), a federal and state government funded national metabolomics service facility and now leads the MA node at the University of Melbourne.
Identifying novel salinity tolerance mechanisms by spatial analysis of lipids in barley roots
(Marica Hall, Jun 26th, 08:40)

Abstract: Ute Roessner

Insuk Lee
Insuk Lee is an Associate Professor of Department of Biotechnology at Yonsei University. He obtained his Ph.D. from the University of Texas at Austin in 2002, and conducted postdoctoral research under EM Marcotte at Center for Systems and Synthetic Biology, University of Texas at Austin. Currently his research focuses on big biological data mining, integrative gene network modeling, and systems genetics. He is the developer of a series of gene-network analysis platforms such as AraNet, WormNet and HumanNet and spearheads the field of omics-data integration.
Googling Biology using Gene Networks
(Dai-ichi Tsuru, Jun 26th, 08:40)

Abstract: Insuk Lee

Pieter Dorrestein
Pieter Dorrestein is the Director of the Therapeutic Discovery Mass Spectrometry Center and a Co-Director, Institute for Metabolomics Medicine in the Skaggs School of Pharmacy & Pharmaceutical Sciences, Departments of Pharmacology, Chemistry and Biochemistry. Dr. Dorrestein was trained by Tadgh Begley in the chemical biology of enzymes involved in vitamin biosynthesis and by Neil Kelleher and Christopher Walsh, whom were co-sponsors of his NRSA postdoctoral fellowship, in Top and Middle down mass spectrometry on proteins that made small molecules of therapeutic value. Since his arrival to UCSD in 2006, Dr. Dorrestein has been pioneering the development of mass spectrometry methods to study the chemical and ecological crosstalk between population of organisms for agricultural, diagnostic and therapeutic applications.
A "GoogleMAP"-type view of specialized molecules from microbes, their communities and hosts including people
(Marica Hall, Jun 26th, 13:40)
 

Abstract: Pieter Dorrestein

Please read the poster presentation guideline carefully. Also, please be aware there are no local commercial print facilities, so please print your poster prior to coming to Tsuruoka.

Click here to download the floor map of exhibition area

Marica East

Read more: Poster Session Marica East 24th June

Please read the poster presentation guideline carefully. Also, please be aware there are no local commercial print facilities, so please print your poster prior to coming to Tsuruoka.

Click here to download the floor map of exhibition area

 

Dai-ichi Ho-oh

Read more: Poster Session Daiichi Ho-oh 24th June

Please read the poster presentation guideline carefully. Also, please be aware there are no local commercial print facilities, so please print your poster prior to coming to Tsuruoka.

Click here to download the floor map of exhibition area

 

Marica East

Read more: Poster Session Marica East 25th June

Please read the poster presentation guideline carefully. Also, please be aware there are no local commercial print facilities, so please print your poster prior to coming to Tsuruoka.

Click here to download the floor map of exhibition area

Dai-ichi Ho-oh

Read more: Poster Session Daiichi Ho-oh 25th June

23rd June

Morning

Effective Metabolomics Software: From Design to Practice

Dai-ichi Tsuru

Organizer: Saravanan Dayalan

Aim and Scope: Good design of scientific software is important. The care and awareness in using such softwareprograms were highlighted in 2006, when a group at Scripps had to retract five papers, including three from Science and one from PNAS due to a problem in their software program(Science 314, 1875;2006). As in other fields of life sciences, software is an intertwined part of Metabolomics. It plays a crucial role in all aspects of the workflow from data generation, management, processing, analysis, and to interpretation.

This workshop is aimed at both software users and developers, with the goal of teaching the fundamentals of efficient software design and development, and best practices in software usage. The speakers provide insights from developing a wide-range of metabolomics software programs.

10:50-11:05 Saravanan Dayalan (Metabolomics Australia, Australia)
11:05-11:20 Janna Hastings (EMBL-EBI, Cambridge UK)
11:20-11:35 Atsushi Fukushima (RIKEN-CSRS, Japan)
11:35-11:50 Jianguo Xia (University of Alberta, Canada)
11:50-12:10 General Discussion

Morning

Metabolomics Measurement Technology and Application (JST-NSF)

Marica Hall

Morning (Marica):

Organizers: Masanori Arita, Oliver Fiehn

Aim and Scope: Metabolomics covers wide range of topics and is effective not only in biomedical fields but also in energy or environmental sciences. This workshop introduces the four research projects under the program title “Metabolomics for a Low Carbon Society,” jointly coordinated by the U.S. National Science Foundation (NSF) and Japan Science and Technology Agency (JST) since 2011. Each talk covers the recent progress including the measurement methods for metabolite identification, software development, and metabolic signalling among plants, insects, and disease. The latter part is dedicated to the worldwide networking efforts.

10:50-11:05 Ryo Nakabayashi (RIKEN-CSRS, Japan)
11:05-11:20 Hiroshi Tsugawa (RIKEN-CSRS, Japan)
11:20-11:35 Sastia Putri (Osaka University, Japan)
11:35-11:50 Ryu Nakata (Kyoto University, Japan)

Introduction to Worldwide Networks
11:50-12:00 PAMM-NET RCN
Lloyd Sumner (Noble Foundation, USA)
12:00-12:10 Ring Trial Initiative and NIH common funds
Oliver Fiehn (UC Davis, USA)

Afternoon

Early-career Member Network of Metabolomics Society

Dai-ichi Tsuru

Abstract are available.
Organizers: The EMN committee of the Metabolomics Society
(Sastia Putri, David Liesenfeld, Thomas Payne, Ralf Weber, Justin van der Hooft, Nicholas Rattray, Evangelia Daskalaki, Gabriel Valbuena, Vincent Asiago)
Session I. Scientific writing and Grant writing: how to get published and funded in metabolomics

This session will deal with something all scientists often face during their career: writing. Three excellent speakers will share their view on how to effectively communicate your science using written language. The different roles these scientists have, i.e., journal editor, part of funding body, part of reviewing committee, promises a vivid and diverse setting of this first session of the workshop. The speakers will concentrate on technical aspects of writing and give some tips focused on early-career scientists. This session aims to provide early-career scientist with tools and resources to work on their writing skills.

Scientific writing
13:40-13:55 Royston Goodacre (University of Manchester, UK)
13:55-14:05 Q&A

Grant writing
14:05-14:15 Krista Zanetti (NIH, USA)
14:15-14-25 Eiichiro Fukusaki (Osaka University, Japan)
14:25-14:35 Q&A
14:40-15:25 Extended Coffee Break (1st floor, exhibition room)
A chance to for the early career members to connect with each other and mingle with top scientists in metabolomics field. Please move to the exhibition area of Dai-ichi Hotel (poster area).
Session II. Identification of unknown metabolites

This session is focused on one of the biggest hurdles facing metabolomics research nowadays. The annotation and identification of unknown metabolites many of you will be confronted with during your metabolomics experiments, is a challenging part of the metabolomics pipeline. In this session, three speakers will explain their approaches and views on this topic and show useful metabolomics databases. The first two speakers will focus on data analysis of gas chromatography coupled to mass spectrometry (GC-MS) spectra and liquid chromatography coupled to high-resolution MS (LC-MS), and the role of NMR in de novo identification will be briefly touched upon. The last speaker will highlight the different metabolomics repositories that are available to the community nowadays. 

This session aims to create an awareness of the different approaches that are out there and the current metabolomics databases that you can use to annotate and identify your metabolites of interest.

15:30-15:45 Oliver Fiehn (UC Davis, USA)
15:45-16:00 David Watson (University of Strathclyde, UK)
16:00-16:15 Ralf Weber (University of Birmingham, UK)
16:15-16:40 Interactive discussion

Afternoon

Metabolomics data standards, data capture and exchange

Marica Hall

Organizers: Reza Salek, Christoph Steinbeck, Susanna-Assunta Sansone, Alejandra Gonzalez-Beltran, Philippe Rocca-Serra, and the COSMOS consortium
Session I. Data Standardization
13:40-13:55 Reza Salek (EMBL-EBI, UK)
13:55-14:20 Steffen Neumann
(Leibniz Institute of Plant Biochemistry, Halle Germany)
14:10-14:25 Kenny Billiau (MPI-MP Golm, Germany)
14:20-14:40 Philippe Rocca-Serra
Alejandra Gonzalez-Beltran
(Oxford e-Research Centre, UK)
14:40-15:00 Discussion and questions
Session II. Data Dissemination, Standardization and Exchange
15:20-15:50 Scott Edmunds(Gigascience) 
Rob Davidson (Gigascience)
Susanna-Assunta Sansone (Nature Scientific Data)
15:50-16:10 Reza Salek (EMBL-EBI, UK)
Philippe Rocca-Serra (Oxford e-Research Centre, UK)
16:10-16:25 Padma Maruvada (NIH/NIDDK, USA)
16:25-16:40 Discussion and questions

Luncheons (12:30-13:20)

Please register to either symposia each day through the registration system. Lunch boxes will be supplied by the vendors only for delegates registered for these symposia. The organizers will not supply lunch to delegates who have not registered for the symposia.

23rd June

Leco LOGO-small

Dai-ichi Tsuru

GC-TOF-MS-based metabolomics for plant science ‒ from starting up of the analytical pipeline to carrying out metabolite profiling

Miyako Kusano

RIKEN-CSRS

Bruker logo rgb 300dpi

Marica Hall

Large-scale Computational and Empirical Annotation of the Medicago Metabolome using UHPLC-MS-SPE-NMR

Lloyd W. Sumner

Noble Foundation

Assure-RMS: A suite of tools for targeted and non-targeted NMR-based analysis in automation

Michelle Markus

Bruker Biospin, Billerica

Bodyfluid-NMR with IVDr systems

Claire Cannet

Bruker Biospin, Rheinstetten


24th June

agilent

Dai-ichi Tsuru

Advances in Instrumentation and Software For Pathway Informed Metabolomics and Integrated Biology Analysis

Theodore Sana

PhD, Integrated Metabolomics Program Manager

Untargeted Metabolomics Study of the Plant-Pathogenic Fungus Magnaporthe oryzae by GC x GC x QTOFMS

Sofia Aronova

Senior GC/ Q-TOF Applications Specialist

Using KEGG Pathways to Visualize Meaningful Biological Correlations with LC/MS Datasets

Dan Cuthbertson

PhD, Software Application Engineer

SHIMADZU

Marica Hall

Metabolome analysis for discovering biomarkers of cancers.

Masaru Yoshida

Kobe University


25th June

ABSCIEX

Dai-ichi Tsuru

Using SWATH mode analysis in metabolomics: the advantage of mass spectral deconvolution of high-resolution MS data

Oliver Fiehn

University of California, Davis

HMT

Marica Hall

C-SCOPE: A Quantitative Energy Metabolism Analysis Package for Cells and Tissues

Kenjiro Kami

Human Metabolome Technologies, Inc.


26th June

ThermoScientific GeneralLogo 032-backWhite
See evening session below

Dai-ichi Tsuru

Transforming Metabolomics Research Using Orbitrap Based LCMS Platforms

Waters LOGO

Marica Hall

Metabolomics: from Biomarker Discovery to Molecular Epidemiology

UPLC-TOF/MS Based Metabolic Profiling for Biomarker Research in Human Plasma

Daisuke Saigusa

Tohoku University

Achieving large scale analysis of complex biofluids

Matthew R. Lewis

Imperial College, London


Evening Sessions (17:00-18:20)

24th June

ThermoScientific GeneralLogo 032-backWhite

Dai-ichi Tsuru

Short-talks
1. "Advantages of Capillary Ion Chromatography Coupled with High Resolution Accurate Mass MS to Profile Anionic Polar Metabolites"
2. "Advances in Current Metabolomics Software Offerings: SIEVE, m/z Cloud, and Thermo Scientific™ Compound Discoverer™ software"
3. "Fingerprinting Triacylglycerols in Seed Oils using Orbitrap Mass Spectrometry and Thermo Scientific™ LipidSearch™ Software"

Mixer session (with alcoholic refreshments and snacks), ending with "Kagami Biraki", a Japanese traditional ceremony

 


25th June

ABSCIEX

Marica Hall

(Refreshments are served)

17:00-17:20 Opening and Introduction

17:20-17:50 CESI-MS, an exciting new tool for the analysis of small charged and polar molecules from the cationic metabolome John C. Hudson (University of Regina, Canada)

17:50-18:20 MRM-DIAL: software solution for quantitative metabolomics by means of SWATH technology Hiroshi Tsugawa (RIKEN Center for Sustainable Resource Science, Japan

23rd June

Society Opening Reception: starting at 18:30 in Marica Hall (Washington Hotel 4F)

The Society Reception begins after the plenary talk by Dr. Kazuki Saito (RIKEN, Japan) in Marica Hall. Participation is free for all delegates (except single-day participants). Starter beverage and small snacks will be served, and you can start viewing posters and exhibitions.

 


24th & 25th June

IAB Laboratory Tour: starting at 17:00

The Institute for Advanced Biosciences (IAB), Keio University, is an academic research institute pioneering the new life science field of "Systems Biology", using both experimental and computational biology. You can visit the world's largest CE-MS metabolome facility. The tour time is about 90 miniutes including the courtesy bus ride to IAB.

The tour on 25th is sponsorted by Agilent Technologies, and you may encounter a surprise before conference banquet.

 


25th June

Society Conference Banquet: starting at 18:30 in Tsuru Room (Dai-ichi Hotel 2F)

metabolomics societyagilentYou can enjoy delicacies of Japanese cuisine at the Conference Banquet. Tsuruoka is a city of gastronomy, home of top quality sake (rice wine), vegetables, fish and pork. The event is sponsored by Agilent Technologies and starts with an opening remark by a company representative.

There will be a live performance of Taiko (Japanese drums) by a local group.

 


 

note:

 

Read more: Excursion

23rd & 24th June

Tsuruoka is a castle city, situated in the middle of the Shonai plain, a region known for its beautiful nature and rich heritage. Primarily surrounded by fertile arable land and beautiful mountains, the plain opens westwards onto the rich fishing grounds of the Japan Sea (with stunning sunsets). Tsuroka's location has nurtured a rich and varied culinary culture, which features traditional dishes that accentuate seasonal ingredients. 

As an exclusive offer for Metabolomics 2014, we have teamed up with the city council and over 20 local restaurateurs to offer Tsuruoka International “Noren”. This scheme will allow delegates to experience the finest Shonai cuisine, in a local atmosphere with the uttmost of ease. 

We hope you will get many chances of passing through noren and enjoy both your stay in Tsuruoka and its unique cuisine.

暖簾(Noren) “A decorative fabric hung at the entrance of many small Japanese restaurants or shops”

Further details will be announced soon.

  • AB SCIEX
  • Agilent Technologies
  • Bruker Corporation
  • Human Metabolome Technologies
  • LECO Corporation
  • Shimadzu Corporation
  • Thermo Fisher Scientific, Inc.
  • Waters Corporation